Enzyme III stimulation of cyclic AMP synthesis in an Escherichia coli crp mutant.
نویسنده
چکیده
Cyclic AMP (cAMP) synthesis in Escherichia coli is altered in cAMP receptor protein mutants and in phosphoenolpyruvate:sugar phosphotransferase transport system mutants. The stimulation of cAMP synthesis observed in cAMP receptor protein-deficient mutants is largely dependent upon enzyme III of the phosphoenolpyruvate:sugar phosphotransferase transport system. The phosphoenolpyruvate:sugar phosphotransferase transport system enzyme I is not required for elevated cAMP synthesis. These results suggest that enzyme III plays an important role in regulating adenylate cyclase activity.
منابع مشابه
Cyclic adenosine 5'-monophosphate in Escherichia coli.
INTRODUCTION ................ ROLE OF CYCLIC AMP IN REGULATION OF GENE EXPRESSION .......... A Positive Element in Gene Expression ...................................... CRP .......................... :........................................... Direct stimulation of gene expression ...................................... Possible Role As a Negative Element .........................................
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عنوان ژورنال:
- Journal of bacteriology
دوره 157 3 شماره
صفحات -
تاریخ انتشار 1984